SOX10 Antikörper (AA 147-252)
Kurzübersicht für SOX10 Antikörper (AA 147-252) (ABIN1724911)
Target
Alle SOX10 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 147-252
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Verwendungszweck
- SOX10 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human SOX10 (AA: 147-252) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Sox10 is expressed in primary melanocytic neoplasms of various histologies but not in fibrohistiocytic proliferations and histiocytoses." in: Journal of the American Academy of Dermatology, Vol. 67, Issue 4, pp. 717-26, (2012) (PubMed).
: "Oligodendroglial-specific transcriptional factor SOX10 is ubiquitously expressed in human gliomas." in: Journal of neuro-oncology, Vol. 76, Issue 2, pp. 115-27, (2006) (PubMed).
: "
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Sox10 is expressed in primary melanocytic neoplasms of various histologies but not in fibrohistiocytic proliferations and histiocytoses." in: Journal of the American Academy of Dermatology, Vol. 67, Issue 4, pp. 717-26, (2012) (PubMed).
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- SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))
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Andere Bezeichnung
- SOX10
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Hintergrund
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This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.
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Molekulargewicht
- 49.9 kDa
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Gen-ID
- 6663
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UniProt
- P56693
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Pathways
- Chromatin Binding
Target
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