IGFBP7 Antikörper (AA 52-156)

Produktnummer ABIN1724902

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IGFBP7 in ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für IGFBP7 Antikörper (AA 52-156) (ABIN1724902)

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGFBP7 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 5A4A9

Produktdetails anti-IGFBP7 Antikörper

Bindungsspezifität: AA 52-156

Verwendungszweck: IGFBP7 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human IGFBP7 (AA: 52-156) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-IGFBP7 Antikörper (ABIN1724902)

Evdokimova, Tognon, Benatar, Yang, Krutikov, Pollak, Sorensen, Seth: "IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors." in: Science signaling, Vol. 5, Issue 255, pp. ra92, (2012) (PubMed).

Details zu IGFBP7

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Andere Bezeichnung: IGFBP7

Hintergrund: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).

Molekulargewicht: 29.1 kDa

UniProt: Q16270

Pathways: Growth Factor Binding