DIS3L2 Antikörper (AA 27-250)
Kurzübersicht für DIS3L2 Antikörper (AA 27-250) (ABIN1724900)
Target
Alle DIS3L2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 27-250
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Verwendungszweck
- DIS3L2 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human DIS3L2 (AA: 27-250) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Cytoskeleton: Formins induce nuclear actin assembly." in: Nature reviews. Molecular cell biology, Vol. 14, Issue 6, pp. 328, (2013) (PubMed).
: "Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility." in: Nature genetics, Vol. 44, Issue 3, pp. 277-84, (2012) (PubMed).
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: "Cytoskeleton: Formins induce nuclear actin assembly." in: Nature reviews. Molecular cell biology, Vol. 14, Issue 6, pp. 328, (2013) (PubMed).
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- DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))
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Andere Bezeichnung
- DIS3L2
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Hintergrund
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The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene.
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Molekulargewicht
- 99.3 kDa
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Gen-ID
- 129563
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UniProt
- Q8IYB7
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Pathways
- Stem Cell Maintenance
Target
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