Decorin Antikörper (AA 263-324)

Produktnummer ABIN1724878

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Decorin in ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für Decorin Antikörper (AA 263-324) (ABIN1724878)

Target: Decorin (DCN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Decorin Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 1G4C5

Produktdetails anti-Decorin Antikörper

Bindungsspezifität: AA 263-324

Verwendungszweck: DCN Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human DCN (AA: 263-324) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Decorin Antikörper (ABIN1724878)

Buraschi, Neill, Owens, Iniguez, Purkins, Vadigepalli, Evans, Schaefer, Peiper, Wang, Iozzo: "Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model." in: PLoS ONE, Vol. 7, Issue 9, pp. e45559, (2012) (PubMed).

Adam, Saller, Ströbl, Hennebold, Dissen, Ojeda, Stouffer, Berg, Berg, Mayerhofer: "Decorin is a part of the ovarian extracellular matrix in primates and may act as a signaling molecule." in: Human reproduction (Oxford, England), Vol. 27, Issue 11, pp. 3249-58, (2012) (PubMed).

Details zu Decorin

Target: Decorin (DCN)

Andere Bezeichnung: DCN

Hintergrund: The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.

Molekulargewicht: 39.7 kDa

Gen-ID: 1634

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process