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Osteoactivin Antikörper (AA 31-260)

Name: Osteoactivin Antikörper (AA 31-260)
Brand: antibodies-online
SKU: ABIN1724859
Price: 640.59 EUR
Availability: InStock

Dieses Anti-Osteoactivin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Osteoactivin in WB, ELISA und IHC. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Western blot analysis using GPNMB mouse mAb against PANC1 (1) and PC-3 (2) cell lysate. (Osteoactivin Antikörper (AA 31-260))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (Osteoactivin Antikörper (AA 31-260))

ELISA

Western blot analysis using GPNMB mAb against human GPNMB recombinant protein. (Osteoactivin Antikörper (AA 31-260))

Western blot analysis using GPNMB mAb against HEK293 (1) and GPNMB (AA: 31-260)-hIgGFc transfected HEK293 (2) cell lysate. (Osteoactivin Antikörper (AA 31-260))

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using GPNMB mouse mAb with DAB staining. (Osteoactivin Antikörper (AA 31-260))

IHC

Immunohistochemical analysis of paraffin-embedded esophagus cancer tissues using GPNMB mouse mAb with DAB staining. (Osteoactivin Antikörper (AA 31-260))

IHC

6 Abbildungen

(2 Referenzen)

Produktnummer ABIN1724859

Kurzübersicht für Osteoactivin Antikörper (AA 31-260) (ABIN1724859)

Target

Alle Osteoactivin (GPNMB) Antikörper anzeigen

Osteoactivin (GPNMB)

Reaktivität

Human

Wirt

Maus

Klonalität

Monoklonal

Konjugat

Dieser Osteoactivin Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon

7C10E5

Bindungsspezifität
15

8

5

3

2

2

2

1

1

1

1

1

1

1

1
AA 31-260

Verwendungszweck

GPNMB Antibody

Aufreinigung

Purified antibody

Immunogen

Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. Coli.

Isotyp

IgG1
anti-Osteoactivin (GPNMB) (AA 81-180) antibody
GPNMB Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Osteoactivin (GPNMB) (AA 104-203) antibody
GPNMB Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1A8 unconjugated

anti-Osteoactivin (GPNMB) (N-Term) antibody
GPNMB Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Osteoactivin (GPNMB) (AA 541-569), (C-Term) antibody
GPNMB Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB36977 unconjugated

anti-Osteoactivin (GPNMB) (AA 104-203) antibody
GPNMB Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated

anti-Osteoactivin (GPNMB) (AA 22-260) antibody
GPNMB Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

anti-Osteoactivin (GPNMB) (AA 50-99) antibody
GPNMB Reaktivität: Human, Maus, Rind (Kuh), Pferd, Kaninchen, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Osteoactivin (GPNMB) (AA 1-572) antibody
GPNMB Reaktivität: Human WB, ELISA, IHC, IHC (p) Wirt: Maus Monoclonal 3A5 unconjugated

anti-Osteoactivin (GPNMB) (AA 1-572) antibody
GPNMB Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3A5 unconjugated

anti-Osteoactivin (GPNMB) (AA 74-123) antibody
GPNMB Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Hund, Kaninchen, Zebrafisch (Danio rerio), Hamster, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

ELISA: 1/10000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Tsui, Chang, Feng, Chang, Juang: "Glycoprotein transmembrane nmb: an androgen-downregulated gene attenuates cell invasion and tumorigenesis in prostate carcinoma cells." in: The Prostate, Vol. 72, Issue 13, pp. 1431-42, (2012) (PubMed).

Williams, Esmaeli, Soheili, Simantov, Gombos, Bedikian, Hwu: "GPNMB expression in uveal melanoma: a potential for targeted therapy." in: Melanoma research, Vol. 20, Issue 3, pp. 184-90, (2010) (PubMed).
Target

Osteoactivin (GPNMB)

Andere Bezeichnung

GPNMB

Hintergrund

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

64 kDa

UniProt

Q14956