NG2 Antikörper (AA 2247-2308)
Kurzübersicht für NG2 Antikörper (AA 2247-2308) (ABIN1724837)
Target
Alle NG2 (MCSP) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 2247-2308
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Verwendungszweck
- CSPG4 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human CSPG4 (AA: 2247-2308) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." in: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).
: "CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma." in: Pigment cell & melanoma research, Vol. 24, Issue 6, pp. 1148-57, (2011) (PubMed).
: "
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Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." in: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).
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- NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
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Andere Bezeichnung
- CSPG4
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Hintergrund
- A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
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Molekulargewicht
- 250.0 kDa
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Gen-ID
- 1464
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UniProt
- Q6UVK1
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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