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NG2 Antikörper (AA 2247-2308)

MCSP Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 7G4E5 unconjugated
Produktnummer ABIN1724837
  • Target Alle NG2 (MCSP) Antikörper anzeigen
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Bindungsspezifität
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2247-2308
    Reaktivität
    • 49
    • 19
    • 16
    Human
    Wirt
    • 38
    • 19
    Maus
    Klonalität
    • 30
    • 26
    • 1
    Monoklonal
    Konjugat
    • 33
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser NG2 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 17
    • 17
    • 10
    • 9
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    CSPG4 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CSPG4 (AA: 2247-2308) expressed in E. Coli.
    Klon
    7G4E5
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wang, Katayama, Wang, Yu, Favoino, Sakakura, Favole, Tsuchikawa, Silver, Watkins, Kageshita, Ferrone: "Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." in: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).

    Price, Colvin Wanshura, Yang, Carlson, Xiang, Li, Ferrone, Dudek, Turley, McCarthy: "CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma." in: Pigment cell & melanoma research, Vol. 24, Issue 6, pp. 1148-57, (2011) (PubMed).

  • Target
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Andere Bezeichnung
    CSPG4 (MCSP Produkte)
    Hintergrund
    A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
    Molekulargewicht
    250.0 kDa
    Gen-ID
    1464
    UniProt
    Q6UVK1
    Pathways
    Glycosaminoglycan Metabolic Process
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