NG2 Antikörper

Produktnummer ABIN5526901

Produktdetails anti-NG2 Antikörper

Target: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Spezifität: The mouse monoclonal antibody 7.1 recognizes an extracellular epitope of NG2, the melanoma-associated chondroitin sulfate proteoglycan 4 of Mw approximately 220-300 kDa.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Human bone marrow stromal cells infected with SV-40

Klon: 7-1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu NG2

Target: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Andere Bezeichnung: NG2 / Chondroitin sulfate proteoglycan 4 (MCSP Produkte)

Synonyme: HMW-MAA antikoerper, MCSP antikoerper, MCSPG antikoerper, MEL-CSPG antikoerper, MSK16 antikoerper, NG2 antikoerper, 4732461B14Rik antikoerper, AN2 antikoerper, Ng2 antikoerper, HSMCSGEN1 antikoerper, MCS antikoerper, chondroitin sulfate proteoglycan 4 antikoerper, sperm mitochondria associated cysteine rich protein antikoerper, CSPG4 antikoerper, Cspg4 antikoerper, SMCP antikoerper

Hintergrund: Chondroitin sulfate proteoglycan 4,NG2 / chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.,Chondroitin sulfate proteoglycan 4, MSK16, CSPG4, MCSP

Gen-ID: 1464

UniProt: Q6UVK1

Pathways: Glycosaminoglycan Metabolic Process