KLF1 Antikörper (AA 208-362)
Kurzübersicht für KLF1 Antikörper (AA 208-362) (ABIN1724828)
Target
Alle KLF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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                                            Bindungsspezifität
- AA 208-362
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                                            Verwendungszweck
- KLF1 Antibody
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                                            Aufreinigung
- Purified antibody
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                                            Immunogen
- Purified recombinant fragment of human KLF1 (AA: 208-362) expressed in E. Coli.
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                                            Isotyp
- IgG1
 
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                                            Applikationshinweise
- 
                        ELISA: 1/10000 FCM: 1/200 - 1/400 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
 
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    - 
                                            : "Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding."    in: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24819-27, (2011)         (PubMed).        
 : "KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching." in: Nature genetics, Vol. 42, Issue 9, pp. 742-4, (2010) (PubMed).
 
 
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                                            : "Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding."    in: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24819-27, (2011)         (PubMed).        
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    - KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))
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                                            Andere Bezeichnung
- KLF1
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                                            Hintergrund
- 
                        This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. 
 
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                                            Molekulargewicht
- 38.2 kDa
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                                            UniProt
- Q13351
 Target
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