MRPL42 Antikörper (AA 142-203)

Produktnummer ABIN1724803

Dieses Maus Monoklonal-Antikörper erkennt spezifisch MRPL42 in ELISA, IHC, WB, FACS und ICC. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für MRPL42 Antikörper (AA 142-203) (ABIN1724803)

Target: MRPL42 (Mitochondrial Ribosomal Protein L42 (MRPL42))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MRPL42 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: 3H6G11

Produktdetails anti-MRPL42 Antikörper

Bindungsspezifität: AA 142-203

Verwendungszweck: MRPL42 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human MRPL42 (AA: 142-203) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-MRPL42 Antikörper (ABIN1724803)

Zhang, Gerstein: "Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome." in: Genomics, Vol. 81, Issue 5, pp. 468-80, (2003) (PubMed).

Koc, Burkhart, Blackburn, Moyer, Schlatzer, Moseley, Spremulli: "The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present." in: The Journal of biological chemistry, Vol. 276, Issue 47, pp. 43958-69, (2001) (PubMed).

Details zu MRPL42

Target: MRPL42 (Mitochondrial Ribosomal Protein L42 (MRPL42))

Andere Bezeichnung: MRPL42

Hintergrund: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.

Molekulargewicht: 16.7 kDa

Gen-ID: 28977

UniProt: Q9Y6G3