Dieses Anti-NEUROD1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von NEUROD1 in ELISA. Geeignet für Human, Maus und Affe. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Huang, Kishida, Cao, Murakami-Tonami, Mu, Nakaguro, Koide, Takeuchi, Onishi, Kadomatsu: "The neuronal differentiation factor NeuroD1 downregulates the neuronal repellent factor Slit2 expression and promotes cell motility and tumor formation of neuroblastoma." in: Cancer research, Vol. 71, Issue 8, pp. 2938-48, (2011) (PubMed).
Shimoda, Chen, Noguchi, Matsumoto, Grayburn: "Neurogenic differentiation 1 directs differentiation of cytokeratin 19-positive human pancreatic nonendocrine cells into insulin-producing cells." in: Transplantation proceedings, Vol. 42, Issue 6, pp. 2071-4, (2010) (PubMed).
Target
NEUROD1
(Neuronal Differentiation 1 (NEUROD1))
Andere Bezeichnung
Neurod
Hintergrund
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.