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Androgen Receptor Antikörper

This anti-Androgen Receptor antibody (ABIN1724724) is a Mouse Monoclonal antibody detecting Androgen Receptor in WB, IHC, ELISA. Suitable for Human.
Produktnummer ABIN1724724

Kurzübersicht für Androgen Receptor Antikörper (ABIN1724724)

Target

Alle Androgen Receptor (AR) Antikörper anzeigen
Androgen Receptor (AR)

Reaktivität

  • 308
  • 98
  • 93
  • 29
  • 17
  • 17
  • 15
  • 12
  • 8
  • 4
  • 4
  • 3
  • 1
Human

Wirt

  • 258
  • 58
  • 1
  • 1
  • 1
Maus

Klonalität

  • 242
  • 75
Monoklonal

Konjugat

  • 133
  • 27
  • 11
  • 11
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 5
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser Androgen Receptor Antikörper ist unkonjugiert

Applikation

  • 191
  • 79
  • 67
  • 65
  • 53
  • 42
  • 28
  • 23
  • 23
  • 22
  • 19
  • 19
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon

2H8
  • Verwendungszweck

    Androgen receptor Antibody

    Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of human AR expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Yu, Han, Shao, Wu, Zhao, Liu, Sun, Tang, Xia: "Androgen receptor functioned as a suppressor in the prostate cancer cell line PC3 in vitro and in vivo." in: Chinese medical journal, Vol. 122, Issue 22, pp. 2779-83, (2009) (PubMed).

    Hsu, Lan, Tsai, Ou, Cheng, Tsai, Kang, Tung, Wong, Huang: "Expression of androgen receptor in human placentas from normal and preeclamptic pregnancies." in: Taiwanese journal of obstetrics & gynecology, Vol. 48, Issue 3, pp. 262-7, (2009) (PubMed).

    Tillman, Yuan, Gu, Fazli, Ghosh, Flynt, Gleave, Rennie, Kasper: "DJ-1 binds androgen receptor directly and mediates its activity in hormonally treated prostate cancer cells." in: Cancer research, Vol. 67, Issue 10, pp. 4630-7, (2007) (PubMed).

  • Target

    Androgen Receptor (AR)

    Andere Bezeichnung

    Androgen receptor

    Hintergrund

    The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression, however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.

    Molekulargewicht

    110 kDa

    Gen-ID

    367

    UniProt

    P10275

    Pathways

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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