Ret Proto-Oncogene Antikörper (AA 896-1063)

Produktnummer ABIN1724678

Der Maus Monoklonal Anti-Ret Proto-Oncogene-Antikörper wurde für ELISA validiert. Er ist geeignet, Ret Proto-Oncogene in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Ret Proto-Oncogene Antikörper (AA 896-1063) (ABIN1724678)

Target: Ret Proto-Oncogene (RET)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ret Proto-Oncogene Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 8D10C9

Produktdetails anti-Ret Proto-Oncogene Antikörper

Bindungsspezifität: AA 896-1063

Verwendungszweck: RET Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of RET (aa896-1063) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Ret Proto-Oncogene Antikörper (ABIN1724678)

Young, Anderson, Anderson: "Guidance cues involved in the development of the peripheral autonomic nervous system." in: Autonomic neuroscience : basic & clinical, Vol. 112, Issue 1-2, pp. 1-14, (2004) (PubMed).

Myers, Mulligan: "The RET receptor is linked to stress response pathways." in: Cancer research, Vol. 64, Issue 13, pp. 4453-63, (2004) (PubMed).

Details zu Ret Proto-Oncogene

Target: Ret Proto-Oncogene (RET)

Andere Bezeichnung: RET

Hintergrund: RET (ret proto-oncogene) is a member of the cadherin superfamily and a receptor tyrosine kinase, which are cell-surface molecules that transduce signals for cell growth and differentiation. It can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Ligands that bind the Ret receptor include the glial cell line-derived neurotropic factor (GDNF) and its congeners neurturin, persephin and artemin. Alterations in the corresponding Ret gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma and a congenital developmental disorder known as Hirschsprung

Gen-ID: 5979

UniProt: P07949

Pathways: RTK Signalweg, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation