CD31 Antikörper

Produktnummer ABIN1724665

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD31 in IHC, ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für CD31 Antikörper (ABIN1724665)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD31 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Klon: 2F7B2

Produktdetails anti-CD31 Antikörper

Verwendungszweck: CD31 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CD31 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-CD31 Antikörper (ABIN1724665)

Wynne, Ball, McLellan, Dockery, Zimmermann, Moore: "Mouse pregnancy-specific glycoproteins: tissue-specific expression and evidence of association with maternal vasculature." in: Reproduction (Cambridge, England), Vol. 131, Issue 4, pp. 721-32, (2006) (PubMed).

Bingle, Lewis, Corke, Reed, Brown: "Macrophages promote angiogenesis in human breast tumour spheroids in vivo." in: British journal of cancer, Vol. 94, Issue 1, pp. 101-7, (2006) (PubMed).

Mayr, Zou, Zhang, Dietrich, Hu, Xu: "Accelerated arteriosclerosis of vein grafts in inducible NO synthase(-/-) mice is related to decreased endothelial progenitor cell repair." in: Circulation research, Vol. 98, Issue 3, pp. 412-20, (2006) (PubMed).

Details zu CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Andere Bezeichnung: CD31

Hintergrund: CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors.It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. The antibody reacts with the murine form of the Platelet-Endothelial Cell Adhesion Molecule. The reactivity of the antibody is restricted to the isoform of the molecule that is selectively expressed by endothelial cells.The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1.It is also weakly expressed on many peripheral lymphoid cells and platelets.CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).

Gen-ID: 5175

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization