EPH Receptor A2 Antikörper

Produktnummer ABIN1724651

Der Maus Monoklonal Anti-EPH Receptor A2-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, EPH Receptor A2 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für EPH Receptor A2 Antikörper (ABIN1724651)

Target: EPH Receptor A2 (EPHA2)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPH Receptor A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 1B3C7

Produktdetails anti-EPH Receptor A2 Antikörper

Verwendungszweck: EphA2 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of EphA2 expressed in E. Coli.

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-EPH Receptor A2 Antikörper (ABIN1724651)

Abraham, Knapp, Cheng, Snyder, Mittal, Bangari, Kinch, Wu, Dhariwal, Mohammed: "Expression of EphA2 and Ephrin A-1 in carcinoma of the urinary bladder." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 2, pp. 353-60, (2006) (PubMed).

Landen, Kinch, Sood: "EphA2 as a target for ovarian cancer therapy." in: Expert opinion on therapeutic targets, Vol. 9, Issue 6, pp. 1179-87, (2005) (PubMed).

Details zu EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Andere Bezeichnung: EphA2

Hintergrund: EPH receptor A2 (EphA2), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, EphA10, EphB1, EphB2, EphB3, EphB4 and EphB6 are Eph family receptors for Ephrin family ligands. In normal cells, EphA2 negatively regulates cell growth and invasiveness. EphA2 is overexpressed by many human cancers, and is often associated with poor prognostic features. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers.EphA2 may serve as a novel target for bladder cancer, colonic adenocarcinoma and ovarian cancer therapy.

Gen-ID: 1969

UniProt: P29317

Pathways: RTK Signalweg