GIT1 Antikörper (C-Term)
Kurzübersicht für GIT1 Antikörper (C-Term) (ABIN1721531)
Target
Alle GIT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 375-770, C-Term
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Spezifität
- Reacts with human GIT1. Cross-reacts with mouse and rat protein.
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Aufreinigung
- Purified (protein G)
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Immunogen
- Fusion protein corresponding to aa 375-770 (C-terminus) of rat GIT1 (accession no.Q9Z272).
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Isotyp
- IgG1
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Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB(1 μg/mL)
Positive control: Rat brain lysate. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, glycerol 50 % .
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Dilute in PBS or medium that is identical to that used in the assay system.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- GIT1
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Andere Bezeichnung
- GIT1
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Hintergrund
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G-protein coupled receptor (GPCR) kinase interacting proteins 1 and 2 (GIT1 and GIT2) are highly conserved ubiquitous scaffold proteins involved in localized signaling to help regulate focal contact assembly and cytoskeletal dynamics. GIT proteins contain multiple interaction domains for small GTPases, kinases, the Rho family GEF PIX, and the focal adhesion protein paxillin. GIT1 is localized to focal adhesions, cytoplasmic complexes and membrane protrusions, and it regulates cell protrusion formation and cell migration.
ARF GTPase-activating protein GIT1, ARF GAP GIT1 Cool-associated and tyrosine-phosphorylated protein 1, CAT-1, CAT1 G protein-coupled receptor kinase-interactor 1 GRK-interacting protein 1 Gene name : GIT1 -
Gen-ID
- 28964
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UniProt
- Q9Y2X7
Target
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