GABBR2 Antikörper (AA 861-912)

Produktnummer ABIN1721530

Dieser Maus Monoklonal Antikörper detektiert spezifisch GABBR2 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für GABBR2 Antikörper (AA 861-912) (ABIN1721530)

Target: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Reaktivität: Human, Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GABBR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: S81-2

Produktdetails anti-GABBR2 Antikörper

Bindungsspezifität: AA 861-912

Spezifität: Reacts with human GABA(B)R2. Cross-reacts with mouse and rat protein. Do not cross-react with GABA(B)R1.

Aufreinigung: Purified (protein G)

Immunogen: Fusion protein corresponding to aa 861-912 of rat GABA(B)R2 (accession no. NP_113990.1).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC(1 -5 μg/mL) WB(1 - 2 μg/mL)

Positive control: Rat brain membranes.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, glycerol 50 % .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute in PBS or medium that is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GABBR2

Target: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Andere Bezeichnung: GABA(B)R2

Hintergrund: GABA (γ-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B), and GABA(C). GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission. Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 in which GABA(B)R1 binds a ligand and GABA(B)R2 is the primary G protein contact site.

Gamma-aminobutyric acid type B receptor subunit 2 GABA-B receptor 2 GABA-B-R2, GABA-BR2, GABABR2, Gb2 G-protein coupled receptor 51 HG20 Gene name : GABBR2

Gen-ID: 9568

UniProt: O75899

Pathways: cAMP Metabolic Process