Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) Antikörper

Produktnummer ABIN1721485

Dieser Maus Monoklonal Antikörper detektiert spezifisch Cav3.1 Ca2+ Channel in IHC und WB. Es zeigt Reaktivität gegenüber Proben von Maus, Human und Ratte.

Kurzübersicht für Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) Antikörper (ABIN1721485)

Target: Cav3.1 Ca2+ Channel

Reaktivität: Maus, Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Klon: S178A-9

Produktdetails

Bindungsspezifität: AA 2052-2172, C-Term

Spezifität: Reacts withhuman, mouse, and rat Cav3.1. Does not cross-react with Cav3.2.

Aufreinigung: Purified

Immunogen: Fusion protein corresponding to aa 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (accession no. NP_001106284.1).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1 - 2 μg/mL) IHC(1 - 10 μg/mL)

Positive control: Rat brain membranes

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute in PBS or medium that is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Cav3.1 Ca2+ Channel

Hintergrund: Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Cav3.1 is a low-voltage activated T-type calcium channel expressed throughout the body. Drugs that block T-type calcium channels are used as antihypertensives and anti-epileptics and possibly in some anesthetics and antipsychotics.

Voltage-dependent T-type calcium channel subunit alpha-1G Cav3.1c NBR13 Voltage-gated calcium channel subunit alpha Cav3.1 Gene name: CACNA1G, KIAA1123 Ca(V)T.1, Cav3.1, NBR13

Gen-ID: 8913

UniProt: O43497