Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) Antikörper
Kurzübersicht für Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) Antikörper (ABIN1098196)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 2052-2172, C-Term
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Verwendungszweck
- Anti-Cav3.1 Ca+2 Channel Mouse Monoclonal Antibody
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Spezifität
- This antibody recognizes human, mouse, and rat Cav3.1. It does not cross-react with Cav3.2.
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Kreuzreaktivität
- Human, Maus, Ratte
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Kreuzreaktivität (Details)
- No cross Reactivity with Cav3.2
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Aufreinigung
- Purified by Protein G affinity chromatography.
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Immunogen
- Fusion protein corresponding to aa 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (accession no. NP_001106284.1).
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Isotyp
- IgG1
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Applikationshinweise
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Immunoblotting: use at 1-2 μg/mL. A band of >200 kDa is detected.
Immunohistochemistry: use at 1-10 μg/mL.
These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: Rat brain membranes. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Rekonstitution
- Dilute in PBS or medium which is identical to that used in the assay system.
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Konzentration
- Lot specific
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Buffer
- PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- This antibody is stable for at least one (1) year at -20°C.
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- Cav3.1 Ca2+ Channel
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Andere Bezeichnung
- Cav3.1 Ca+2 Channel
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Hintergrund
- Voltage-dependent T-type calcium channel subunit α,Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Cav3.1 is a low-voltage- activated T-type calcium channel expressed throughout the body. Drugs that block T-type calcium channels are used as antihypertensives and antiepileptics and possibly in some anesthetics and antipsychotics.
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NCBI Accession
- NP_001106284
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UniProt
- Q9WUT2
Target
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