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Chemerin Antikörper (AA 101-163)

Der Kaninchen Polyklonal Anti-Chemerin-Antikörper wurde für WB, ELISA, IF (cc), IF (p), ICC, IHC (fro) und IHC (p) validiert. Er ist geeignet, Chemerin in Proben von Ratte zu detektieren. Es sind 3+ Publikationen verfügbar.
Produktnummer ABIN1715135

Kurzübersicht für Chemerin Antikörper (AA 101-163) (ABIN1715135)

Target

Alle Chemerin (RARRES2) Antikörper anzeigen
Chemerin (RARRES2) (Retinoic Acid Receptor Responder (Tazarotene Induced) 2 (RARRES2))

Reaktivität

  • 36
  • 34
  • 23
  • 15
Ratte

Wirt

  • 47
  • 7
  • 5
Kaninchen

Klonalität

  • 49
  • 10
Polyklonal

Konjugat

  • 23
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser Chemerin Antikörper ist unkonjugiert

Applikation

  • 50
  • 25
  • 25
  • 18
  • 8
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 15
    • 14
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 101-163

    Kreuzreaktivität

    Ratte

    Homologie

    Cow,Pig,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from rat chemerin

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Gonzalvo-Feo, Del Prete, Pruenster, Salvi, Wang, Sironi, Bierschenk, Sperandio, Vecchi, Sozzani: "Endothelial cell-derived chemerin promotes dendritic cell transmigration." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 5, pp. 2366-73, (2014) (PubMed).

    Akamata, Asano, Taniguchi, Yamashita, Saigusa, Nakamura, Noda, Aozasa, Toyama, Takahashi, Ichimura, Sumida, Tada, Sugaya, Kadono, Sato: "Increased expression of chemerin in endothelial cells due to Fli1 deficiency may contribute to the development of digital ulcers in systemic sclerosis." in: Rheumatology (Oxford, England), (2014) (PubMed).

    Krautbauer, Wanninger, Eisinger, Hader, Beck, Kopp, Schmid, Weiss, Dorn, Buechler: "Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver." in: Experimental and molecular pathology, Vol. 95, Issue 2, pp. 199-205, (2013) (PubMed).

  • Target

    Chemerin (RARRES2) (Retinoic Acid Receptor Responder (Tazarotene Induced) 2 (RARRES2))

    Andere Bezeichnung

    Chemerin

    Hintergrund

    Synonyms: Rarres2, TIG2, tazarotene induced gene 2, Retinoic acid receptor responder protein 2, Tazarotene-induced gene 2 protein, RAR-responsive protein TIG2, Chemerin.

    Background: Chemerin, also known as retinoic acid receptor responder 2 (RARRES2) and tazarotene induced gene 2 (TIG2), is a chemoattractant protein for cells expressing G-protein-linked receptor chemokine-like receptor 1 (CMKLR1, ChemR23 or GPCR-DEZ). The protein is synthesized as a secreted precursor, prochemerin (18 kDa), which is poorly active. Upon proteolytic removal of the last six amino acids, prochemerin is converted into mature active chemerin (15-16 kDa) that acts as a strong and highly specific agonist of its receptor CMKLR1. Chemerin is a newly described adipokine with effects on adipocyte differnetiation and metabolism.

    Gen-ID

    297073

    Pathways

    Brown Fat Cell Differentiation
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