Chemerin Antikörper (AA 101-163)
Kurzübersicht für Chemerin Antikörper (AA 101-163) (ABIN1715135)
Target
Alle Chemerin (RARRES2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 101-163
-
Kreuzreaktivität
- Ratte
-
Homologie
- Cow,Pig,Rabbit
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from rat chemerin
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
Haltbarkeit
- 12 months
-
-
-
Endothelial cell-derived chemerin promotes dendritic cell transmigration." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 5, pp. 2366-73, (2014) (PubMed).
: "Increased expression of chemerin in endothelial cells due to Fli1 deficiency may contribute to the development of digital ulcers in systemic sclerosis." in: Rheumatology (Oxford, England), (2014) (PubMed).
: "Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver." in: Experimental and molecular pathology, Vol. 95, Issue 2, pp. 199-205, (2013) (PubMed).
: "
-
Endothelial cell-derived chemerin promotes dendritic cell transmigration." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 5, pp. 2366-73, (2014) (PubMed).
-
- Chemerin (RARRES2) (Retinoic Acid Receptor Responder (Tazarotene Induced) 2 (RARRES2))
-
Andere Bezeichnung
- Chemerin
-
Hintergrund
-
Synonyms: Rarres2, TIG2, tazarotene induced gene 2, Retinoic acid receptor responder protein 2, Tazarotene-induced gene 2 protein, RAR-responsive protein TIG2, Chemerin.
Background: Chemerin, also known as retinoic acid receptor responder 2 (RARRES2) and tazarotene induced gene 2 (TIG2), is a chemoattractant protein for cells expressing G-protein-linked receptor chemokine-like receptor 1 (CMKLR1, ChemR23 or GPCR-DEZ). The protein is synthesized as a secreted precursor, prochemerin (18 kDa), which is poorly active. Upon proteolytic removal of the last six amino acids, prochemerin is converted into mature active chemerin (15-16 kDa) that acts as a strong and highly specific agonist of its receptor CMKLR1. Chemerin is a newly described adipokine with effects on adipocyte differnetiation and metabolism.
-
Gen-ID
- 297073
-
Pathways
- Brown Fat Cell Differentiation
Target
-