Chemerin Antikörper (AA 101-163) (Biotin)

Produktnummer ABIN1701633

Produktdetails anti-Chemerin Antikörper (Biotin)

Target: Chemerin (RARRES2) (Retinoic Acid Receptor Responder (Tazarotene Induced) 2 (RARRES2))

Bindungsspezifität: AA 101-163

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Chemerin Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Ratte

Homologie: Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat chemerin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Referenzen für anti-Chemerin Antikörper (Biotin) (ABIN1701633)

Gonzalvo-Feo, Del Prete, Pruenster, Salvi, Wang, Sironi, Bierschenk, Sperandio, Vecchi, Sozzani: "Endothelial cell-derived chemerin promotes dendritic cell transmigration." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 5, pp. 2366-73, (2014) (PubMed).

Details zu Chemerin

Target: Chemerin (RARRES2) (Retinoic Acid Receptor Responder (Tazarotene Induced) 2 (RARRES2))

Andere Bezeichnung: Chemerin (RARRES2 Produkte)

Synonyme: HP10433 antikoerper, TIG2 antikoerper, 0610007L05Rik antikoerper, AI303516 antikoerper, retinoic acid receptor responder 2 antikoerper, retinoic acid receptor responder (tazarotene induced) 2 antikoerper, RARRES2 antikoerper, Rarres2 antikoerper

Hintergrund:

Synonyms: Rarres2, TIG2, tazarotene induced gene 2, Retinoic acid receptor responder protein 2, Tazarotene-induced gene 2 protein, RAR-responsive protein TIG2, Chemerin.

Background: Chemerin, also known as retinoic acid receptor responder 2 (RARRES2) and tazarotene induced gene 2 (TIG2), is a chemoattractant protein for cells expressing G-protein-linked receptor chemokine-like receptor 1 (CMKLR1, ChemR23 or GPCR-DEZ). The protein is synthesized as a secreted precursor, prochemerin (18 kDa), which is poorly active. Upon proteolytic removal of the last six amino acids, prochemerin is converted into mature active chemerin (15-16 kDa) that acts as a strong and highly specific agonist of its receptor CMKLR1. Chemerin is a newly described adipokine with effects on adipocyte differnetiation and metabolism.

Gen-ID: 297073

Pathways: Brown Fat Cell Differentiation