CD3 epsilon Antikörper (AA 11-100)

Produktnummer ABIN1715134

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch CD3 epsilon in FACS, ELISA, ICC, IHC (fro), IHC (p), IF (p) und IF (cc). Er zeigt eine Reaktivität gegenüber Human, Maus und Schwein und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für CD3 epsilon Antikörper (AA 11-100) (ABIN1715134)

Target: CD3 epsilon (CD3E)

Reaktivität: Human, Maus, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD3 epsilon Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-CD3 epsilon Antikörper

Bindungsspezifität: AA 11-100

Kreuzreaktivität: Human, Maus, Schwein

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from pig CD3E

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CD3 epsilon Antikörper (ABIN1715134)

Zhang, Liu, Xu, Jiang, Zhang, Shi, Chen, Liu, Gu, Zhu, Wu: "Pathophysiology of chronic pancreatitis induced by dibutyltin dichloride joint ethanol in mice." in: World journal of gastroenterology, Vol. 22, Issue 10, pp. 2960-70, (2017) (PubMed).

Takeuchi, Niki, Matsunari, Umeyama, Nagashima, Enomoto, Toyama, Matsumoto, Nakamura et al.: "Temporal Changes in Cellular Repopulation and Collagen Fibril Remodeling and Regeneration After Allograft Anterior Cruciate Ligament Reconstruction: An Experimental Study Using Kusabira-Orange ..." in: The American journal of sports medicine, Vol. 44, Issue 9, pp. 2375-83, (2016) (PubMed).

Details zu CD3 epsilon

Target: CD3 epsilon (CD3E)

Andere Bezeichnung: CD3E

Hintergrund:

Synonyms: CD3, T-cell surface glycoprotein CD3 epsilon chain, CD3e

Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Gen-ID: 397455

UniProt: Q7YRN2

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway