IFNA1 Antikörper (AA 150-189)

Produktnummer ABIN1715112

Dieses Anti-IFNA1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IFNA1 in WB, IF (p) und IHC (p). Geeignet für Maus.

Kurzübersicht für IFNA1 Antikörper (AA 150-189) (ABIN1715112)

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFNA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IFNA1 Antikörper

Bindungsspezifität: AA 150-189

Spezifität: The antibody targets Mouse IFNA1 protein, but will cross-react with IFNA11 and IFNA16

Kreuzreaktivität: Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse IFNA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Andere Bezeichnung: IFNA1

Hintergrund:

Synonyms: IFN alpha, IFN-alpha-1, IFA1, Interferon alpha 1, IFNA1_MOUSE, IFNA11, IFNAB_MOUSE, IFN-alpha-11, Interferon alpha-11, Limitin, Q810G1_MOUSE, IFNA16, IFNA6T

Background: IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages, they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes, and they also increase the ability of uninfected host cells to resist new infection by virus. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. IFNA1 is produced by macrophages and has antiviral activities.

Gen-ID: 15962

UniProt: P01572

Pathways: JAK-STAT Signalweg, Hepatitis C