AGPAT5 Antikörper (AA 188-285)

Produktnummer ABIN1714843

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch AGPAT5 in ELISA, IF (cc), IF (p), IHC (p), IHC (fro) und ICC. Er zeigt eine Reaktivität gegenüber Human und Ratte und wurde in 1 Publikation erwähnt.

Kurzübersicht für AGPAT5 Antikörper (AA 188-285) (ABIN1714843)

Target: AGPAT5 (1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (Lysophosphatidic Acid Acyltransferase, Epsilon) (AGPAT5))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGPAT5 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-AGPAT5 Antikörper

Bindungsspezifität: AA 188-285

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LPAAT-epsilon/AGPAT5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-AGPAT5 Antikörper (ABIN1714843)

Angenendt, Reuter, Kentrup, Benk, Neumann, Hüve, Martens, Schwöppe, Kessler, Schmidt, Sauer, Brand, Mikesch, Lenz, Mesters, Müller-Tidow, Hartmann, Wardelmann, Neri, Berdel, Roesli, Schliemann: "An atlas of bloodstream-accessible bone marrow proteins for site-directed therapy of acute myeloid leukemia." in: Leukemia, Vol. 32, Issue 2, pp. 510-519, (2017) (PubMed).

Details zu AGPAT5

Target: AGPAT5 (1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (Lysophosphatidic Acid Acyltransferase, Epsilon) (AGPAT5))

Andere Bezeichnung: LPAAT-epsilon/AGPAT5

Hintergrund:

Synonyms: 1 acyl sn glycerol 3 phosphate acyltransferase epsilon, 1 acylglycerol 3 phosphate O acyltransferase 5, 1 AGP acyltransferase 5, 1 AGPAT 5, 1 AGPAT5, 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon, 1-acylglycerol-3-phosphate O-acyltransferase 5 lysophosphatidic acid acyltransferase, epsilon, 1-acylglycerol-3-phosphate O-acyltransferase 5, 1-AGP acyltransferase 5, 1-AGPAT 5, 1acylglycerol3phosphate Oacyltransferase 5 lysophosphatidic acid acyltransferase, epsilon, 1acylglycerol3phosphate Oacyltransferase 5, 1acylglycerol3phosphate Oacyltransferase5 lysophosphatidic acid acyltransferase, epsilon, 1AGP acyltransferase 5, 1AGPAT5, AGPAT5, LPAAT e, LPAAT epsilon, LPAAT-epsilon, LPAATE, Lysophosphatidic acid acyltransferase epsilon, PLCE_HUMAN.

Background: Phosphatidic acid and lysophosphatidic acid are phospholipids involved in lipid biosynthesis and signal transduction. LPAAT-epsilon (lysophosphatidic acid acyltransferase epsilon, also designated 1-AGP acyltransferase 5 (AGPAT5)) catalyzes the synthesis of phosphatidic acid from lysophosphatidic acid. LPAAT-epsilon is a membrane-bound protein belonging to the LPAAT family. Members of the LPAAT family have a well-known role in lipid biosynthesis and they may also play a role in tumor progression. LPAAT-epsilon is expressed in a tissue-specific manner in prostate and testis. LPAAT-epsilon is most closely related to AGPAT8, which is highly expressed in heart.

Gen-ID: 55326