ABCA1 Antikörper (pSer2054)

Produktnummer ABIN1714640

Der Kaninchen-Polyklonal Anti-ABCA1-Antikörper wurde für ELISA, ICC, IF (cc), IF (p) und IHC (fro) validiert. Er ist geeignet zum Nachweis von ABCA1 in Proben aus Maus. }

Kurzübersicht für ABCA1 Antikörper (pSer2054) (ABIN1714640)

Target: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCA1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ABCA1 Antikörper

Bindungsspezifität: pSer2054

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human ABCA1 around the phosphorylation site of Ser2054

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ABCA1

Target: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Andere Bezeichnung: ABCA1

Hintergrund:

Synonyms: ABCA1 phospho S2054, p-ABCA1 phospho S2054, ATP binding cassette transporter A1, ABC 1, ABC Transporter 1, ABC1, ABCA 1, ABCA1, ATP binding Cassette 1, ATP binding cassette sub family A ABC1 member 1, ATP binding cassette sub family A member 1, ATP binding cassette sub-family A member 1, ATP binding Cassette Transporter 1, ATP-binding Cassette 1, ATP-binding Cassette Transporter 1, CERP, Cholesterol Efflux Regulatory Protein, FLJ14958, HDLDT1, Membrane bound, MGC164864, MGC165011, TD, TGD, ABCA1_HUMAN.

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.

Gen-ID: 19

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism