LSD1 Antikörper (AA 301-400)

Produktnummer ABIN1714208

Der Kaninchen Polyklonal Anti-LSD1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, LSD1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für LSD1 Antikörper (AA 301-400) (ABIN1714208)

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LSD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-LSD1 Antikörper

Bindungsspezifität: AA 301-400

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KDM1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu LSD1

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Andere Bezeichnung: KDM1

Hintergrund:

Synonyms: Amine oxidase flavin containing domain 2, Amine oxidase flavin containing domain 2, Amine oxidase flavin containing domain protein 2, AOF 2, AOF2, BHC110, BRAF35 HDAC complex protein BHC110, BRAF35-HDAC complex protein BHC110, FAD binding protein BRAF35 HDAC complex, 110 kDa subunit, Flavin containing amine oxidase domain containing protein 2, Flavin-containing amine oxidase domain-containing protein 2, KDM 1, Kdm1a, KDM1A_HUMAN, KIAA0601, LSD 1, LSD1, Lysine K specic demethylase 1, Lysine K specic demethylase 1A, Lysine specic histone demethylase 1, Lysine specic histone demethylase 1A, Lysine-specic histone demethylase 1, Lysine-specic histone demethylase 1A.

Background: Gene activation and repression is specifically regulated by histone methylation status at distinct lysine residues. Lysine specific demethylase 1 (KDM1/LSD1) is a long-sought histone demethylase that specifically demethylates mono and di methyl histone H3 at K4 and K9. Thus KDM1 is a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor.

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effekt