HDAC4 Antikörper (pSer246)

Produktnummer ABIN1713630

Der Kaninchen Polyklonal anti-HDAC4 Antikörper (ABIN1713630) detektiert spezifisch HDAC4 in WB, IF (p) und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für HDAC4 Antikörper (pSer246) (ABIN1713630)

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HDAC4 Antikörper

Bindungsspezifität: pSer246

Aufreinigung: purified by Protein A and peptide affinity chromatography

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HDAC4 around the phosphorylation site of pSer246

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB (1:100-500),IHC-P (1:100-500),IF (p) (1:100-500)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C for 12 months

Haltbarkeit: 12 months

Details zu HDAC4

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Andere Bezeichnung: HDAC4

Hintergrund: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

Gen-ID: 9759

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process