HHAT Antikörper (AA 101-200)

Produktnummer ABIN1713534

Dieser Anti-HHAT Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von HHAT in WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) und ICC. Geeignet für Human.

Kurzübersicht für HHAT Antikörper (AA 101-200) (ABIN1713534)

Target: HHAT (Hedgehog Acyltransferase (HHAT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HHAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-HHAT Antikörper

Bindungsspezifität: AA 101-200

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HHAT

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu HHAT

Target: HHAT (Hedgehog Acyltransferase (HHAT))

Andere Bezeichnung: HHAT

Hintergrund:

Synonyms: 2810432O22Rik, AC115917.1, AI462858, FLJ10724, FLJ34867, Hedgehog acyltransferase, Hhat, HHAT_HUMAN, MART 2, MART-2, MART2, Melanoma antigen recognized by T cells 2, Melanoma antigen recognized by T-cells 2, MGC11697, OTTMUSP00000033669, Protein cysteine N palmitoyltransferase HHAT, Protein-cysteine N-palmitoyltransferase HHAT, RGD1311746, SKI1, Skinny hedgehog protein 1, Skinny hedgehog protein, Skn.

Background: HHAT is a 493 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyze the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8 % of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1.

Gen-ID: 55733

Pathways: Hedgehog Signalweg