IFNAR1 Antikörper (Tyr466) (PE)

Produktnummer ABIN1712792

Der Kaninchen Polyklonal Anti-IFNAR1-Antikörper wurde für FACS validiert. Er ist geeignet, IFNAR1 in Proben von Human zu detektieren.

Kurzübersicht für IFNAR1 Antikörper (Tyr466) (PE) (ABIN1712792)

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFNAR1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-IFNAR1 Antikörper (PE)

Bindungsspezifität: Tyr466

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFNAR1 around the phosphorylation site of Tyr466

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4 °C for 12 months.

Haltbarkeit: 12 months

Details zu IFNAR1

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Andere Bezeichnung: Ifnar1

Hintergrund: IFNAR1 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
Synonyms: Alpha type antiviral protein, AVP, Beta type antiviral protein, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, N alpha REC, N alpha REC, N alpha receptor, N alpha/beta Receptor alpha, N beta receptor, Interferon alpha/beta receptor 1, N-alpha/beta receptor 1, N-R-1, NAR, NAR1, NBR, RC, INAR1_HUMAN, Interferon alpha beta and omega receptor 1, Interferon alpha/beta receptor 1, Interferon alpha/beta receptor alpha chain, Interferon beta receptor 1, Type I interferon receptor 1.

Pathways: JAK-STAT Signalweg, Hepatitis C