KIF13B Antikörper (AA 351-450) (HRP)

Produktnummer ABIN1712558

Der Kaninchen Polyklonal Anti-KIF13B-Antikörper wurde für ELISA, WB, IHC (p) und IHC (fro) validiert. Er ist geeignet, KIF13B in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für KIF13B Antikörper (AA 351-450) (HRP) (ABIN1712558)

Target: KIF13B (Kinesin Family Member 13B (KIF13B))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF13B Antikörper ist konjugiert mit HRP

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-KIF13B Antikörper (HRP)

Bindungsspezifität: AA 351-450

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KIF13B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KIF13B

Target: KIF13B (Kinesin Family Member 13B (KIF13B))

Andere Bezeichnung: KIF13B

Hintergrund:

Synonyms: GAKIN, Guanylate kinase associated kinesin, KI13B_HUMAN, KIAA0639, K 13B, K13B, Kinesin 13B, Kinesin family member 13B, Kinesin like protein GAKIN, Kinesin like protein K13B, Kinesin-like protein GAKIN, Kinesin-like protein K13B, OTTHUMP00000225649.

Background: KIF13B is also known as Kinesin-like protein GAKIN or GAKIN and is a 1,826 amino acid protein that is widely expressed in tissues, with highest expression in brain and kidney. KIF13B is localized to the cytoplasm, as well as to the cytoskeleton, and is thought to be a microtubule-dependent motor protein which is able to bind to a variety of proteins in order to traffic them to various locations throughout the cell. KIF13B belongs to the kinesin-like protein family and possesses three domains typical of the kinesin-like protein family, namely an N-terminal motor domain with an ATP-binding motif, an FHA domain which is known to bind diverse cargos and a large stalk domain involved in protein-protein binding. Additionally, KIF13B has a microtubule-interacting sequence which is known as the CAP-Gly domain at its C-terminus. The CAP-Gly domain is highly conserved domain among eukaryotes, and in humans, defects in the CAP-Gly domain are implicated in many diseases affecting the trafficking of vesicles, neuromuscular junctions and lysosome proliferation.

Gen-ID: 23303

UniProt: Q9NQT8