GNL2 Antikörper (AA 1-100) (HRP)

Produktnummer ABIN1712330

Der Kaninchen Polyklonal Anti-GNL2-Antikörper wurde für ELISA, WB, IHC (fro) und IHC (p) validiert. Er ist geeignet, GNL2 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für GNL2 Antikörper (AA 1-100) (HRP) (ABIN1712330)

Target: GNL2 (Guanine Nucleotide Binding Protein Like Protein 2 (GNL2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNL2 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GNL2 Antikörper (HRP)

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNL2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GNL2

Target: GNL2 (Guanine Nucleotide Binding Protein Like Protein 2 (GNL2))

Andere Bezeichnung: GNL2

Hintergrund:

Synonyms: Autoantigen NGP-1, Autoantigen NGP1, DJ423B22.6 novel nucleolar guanosine 5'-triphosphate binding protein, FLJ40906, GNL2, Guanine nucleotide binding protein-like 2 nucleolar, HUMAUANTIG, NGP1, NOG2_HUMAN, Nucleolar GTP binding protein 2, Nucleolar GTP-binding protein 2, Nucleolar GTPase.

Background: GNL2 is a nucleolar guanasine-triphosphate binding protein that is ubiquitously expressed at low levels in almost all tissues. GNL2 is involved in the crucial process of trafficking proteins out of the nucleus. Specifically, it is a GTPase that interacts with the 60s preribosomal subunit in the nucleus and facilitates export of the subunit into the cytoplasm. GTPases are responsible for the hydrolysis of GTP by way of a protein region dubbed the G domain. GTPases are often involved in the translocating proteins through membranes gleaning energy for the activity by hydrolizing GTP. GNL2 shares G domain homology and some functionality with nucleostemin (GNL3), another nuclear GTPase. Highest expression of GNL2 is found in testis.

Gen-ID: 29889