GNL2 Antikörper (AA 1-100) (Biotin)

Produktnummer ABIN1701313

Produktdetails anti-GNL2 Antikörper (Biotin)

Target: GNL2 (Guanine Nucleotide Binding Protein Like Protein 2 (GNL2))

Bindungsspezifität: AA 1-100

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNL2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNL2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GNL2

Target: GNL2 (Guanine Nucleotide Binding Protein Like Protein 2 (GNL2))

Andere Bezeichnung: GNL2 (GNL2 Produkte)

Synonyme: HUMAUANTIG antikoerper, NGP1 antikoerper, Ngp-1 antikoerper, BC003262 antikoerper, RGD1305006 antikoerper, G protein nucleolar 2 antikoerper, guanine nucleotide binding protein-like 2 (nucleolar) antikoerper, GNL2 antikoerper, Gnl2 antikoerper

Hintergrund:

Synonyms: Autoantigen NGP-1, Autoantigen NGP1, DJ423B22.6 novel nucleolar guanosine 5'-triphosphate binding protein, FLJ40906, GNL2, Guanine nucleotide binding protein-like 2 nucleolar, HUMAUANTIG, NGP1, NOG2_HUMAN, Nucleolar GTP binding protein 2, Nucleolar GTP-binding protein 2, Nucleolar GTPase.

Background: GNL2 is a nucleolar guanasine-triphosphate binding protein that is ubiquitously expressed at low levels in almost all tissues. GNL2 is involved in the crucial process of trafficking proteins out of the nucleus. Specifically, it is a GTPase that interacts with the 60s preribosomal subunit in the nucleus and facilitates export of the subunit into the cytoplasm. GTPases are responsible for the hydrolysis of GTP by way of a protein region dubbed the G domain. GTPases are often involved in the translocating proteins through membranes gleaning energy for the activity by hydrolizing GTP. GNL2 shares G domain homology and some functionality with nucleostemin (GNL3), another nuclear GTPase. Highest expression of GNL2 is found in testis.

Gen-ID: 29889