ESRP2 Antikörper (AA 21-120) (HRP)

Produktnummer ABIN1712046

Dieses Anti-ESRP2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ESRP2 in WB, ELISA, IHC (p) und IHC (fro). Geeignet für Human und Maus.

Kurzübersicht für ESRP2 Antikörper (AA 21-120) (HRP) (ABIN1712046)

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRP2 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ESRP2 Antikörper (HRP)

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ESRP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ESRP2

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Andere Bezeichnung: ESRP2

Hintergrund:

Synonyms: Epithelial splicing regulatory protein 2, ESRP 2, ESRP2, ESRP2_HUMAN, FLJ21918, FLJ22248, RBM35B, RNA binding mot protein 35A, RNA binding mot protein 35B, RNA binding protein 35B, RNA-binding mot protein 35B, RNA-binding protein 35B.

Background: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

Gen-ID: 80004