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Inversin Antikörper (AA 31-130) (HRP)

This anti-Inversin antibody (ABIN1711901) is a Rabbit Polyclonal antibody detecting Inversin in WB, ELISA, IHC (fro), IHC (p). Suitable for Human, Mouse.
Produktnummer ABIN1711901

Kurzübersicht für Inversin Antikörper (AA 31-130) (HRP) (ABIN1711901)

Target

Alle Inversin (INVS) Antikörper anzeigen
Inversin (INVS)

Reaktivität

  • 28
  • 16
  • 2
Human, Maus

Wirt

  • 29
  • 1
Kaninchen

Klonalität

  • 30
Polyklonal

Konjugat

  • 13
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Inversin Antikörper ist konjugiert mit HRP

Applikation

  • 26
  • 13
  • 13
  • 10
  • 10
  • 4
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 14
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 31-130

    Kreuzreaktivität

    Human, Maus

    Homologie

    Rat,Cow,Sheep,Chimpanzee

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Inversin

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Inversin (INVS)

    Andere Bezeichnung

    Inversin

    Hintergrund

    Synonyms: INV, Inversion of embryo turning homolog, inversion of embryonic turning, INVS, Nephrocystin 2, Nephrocystin-2, Nephrocystin2, nephronophthisis 2 infantile, NPH2, NPHP2, INVS_HUMAN.

    Background: Nephrocystin-2 is a 1,065 amino acid protein that exists as three alternatively spliced isoforms and is essential for establishment of the left-right axis and normal renal development. Localizing to the cytoplasm, cytoskeleton, membrane and nucleus, nephrocystin-2 is expressed during presomite-stage embryos and persists in adulthood, with high levels of expression in liver and kidney. Mice expressing nephrocystin-2 mutations are primarily generated by random insertional mutagenesis and result in the reversal of left/right polarity and cyst formation in the kidneys. Furthermore, altered nephrocystin-2 function reverses nodal and lefty expression, indicating that nephrocystin-2 signaling occurs upstream of these proteins involved in the development of asymmetry.

    Gen-ID

    27130
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