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BCL6B Antikörper (AA 141-440) (HRP)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BCL6B in ELISA, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN1710886

Kurzübersicht für BCL6B Antikörper (AA 141-440) (HRP) (ABIN1710886)

Target

Alle BCL6B Antikörper anzeigen
BCL6B (B-Cell CLL/lymphoma 6, Member B (BCL6B))

Reaktivität

  • 28
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 27
  • 3
Kaninchen

Klonalität

  • 30
Polyklonal

Konjugat

  • 11
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BCL6B Antikörper ist konjugiert mit HRP

Applikation

  • 13
  • 13
  • 10
  • 4
  • 2
  • 2
  • 1
ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 141-440

    Homologie

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human BCL6B

    Isotyp

    IgG
  • Applikationshinweise

    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handhabung

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    BCL6B (B-Cell CLL/lymphoma 6, Member B (BCL6B))

    Andere Bezeichnung

    BCL6B

    Hintergrund

    Synonyms: B cell CLL/lymphoma 6, member B zinc finger protein, B-cell CLL/lymphoma 6, member B zinc finger protein, BAZF, Bcl6 associated zinc finger protein, Bcl6-associated zinc finger protein, ZBTB28, Zinc finger protein 62, ZNF62.

    Background: Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NF_B expression, thereby inhibiting NF_B-mediated cellular functions. Bcl-6b (B-cell CLL/lymphoma 6, member B), also known as ZNF62, BAZF or ZBTB28, is a 480 amino acid nuclear protein that contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed ubiquitously with highest expression in placenta and heart, Bcl-6b associates with Bcl-6 and functions as a sequence-specific transcriptional repressor that is thought to be necessary for early B-cell development. The gene encoding Bcl-6b maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.

    Pathways

    BCR Signaling
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