PAG1 Antikörper (AA 331-432) (FITC)
Kurzübersicht für PAG1 Antikörper (AA 331-432) (FITC) (ABIN1709580)
Target
Alle PAG1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 331-432
-
Kreuzreaktivität
- Maus, Ratte
-
Homologie
- Human,Dog,Horse,Rabbit
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human PAG1
-
Isotyp
- IgG
-
-
anti-phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1) (AA 97-432) antibody
PAG1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1) (C-Term) antibodyPAG1 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB, IP, IHC (p) Wirt: Maus Monoclonal PAG-C1 unconjugated
anti-phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1) (AA 97-432) antibodyPAG1 Reaktivität: Human WB, IHC (p), ICFC Wirt: Maus Monoclonal MEM-255 unconjugated
anti-phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1) antibodyPAG1 Reaktivität: Human WB, FACS, ICC Wirt: Kaninchen Monoclonal 24GB685 unconjugated Recombinant Antibody
anti-phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1) (AA 97-432) antibodyPAG1 Reaktivität: Human, Maus WB, IP, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1) (AA 331-432) antibodyPAG1 Reaktivität: Maus, Ratte WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1) (AA 235-280), (AA 97-432) antibodyPAG1 Reaktivität: Human WB, IHC, FACS, IHC (p) Wirt: Maus Monoclonal MEM-255 unconjugated
anti-phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1) (AA 160-390) antibodyPAG1 Reaktivität: Maus WB, IP, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1) (AA 138-357) antibodyPAG1 Reaktivität: Ratte WB, IP, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1) (AA 54-380) antibodyPAG1 Reaktivität: Rind (Kuh) WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
-
FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))
-
Andere Bezeichnung
- Pag1
-
Hintergrund
-
Synonyms: CBP, PAG, Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Csk-binding protein, Transmembrane adapter protein PAG, Transmembrane phosphoprotein Cbp, PAG1
Background: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
-
Gen-ID
- 55824
-
UniProt
- Q9NWQ8
-
Pathways
- p53 Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
Target
-
