HDAC4 Antikörper (pSer246) (Cy7)

Produktnummer ABIN1707521

Der Kaninchen Polyklonal anti-HDAC4 Antikörper wird verwendet zum Nachweis von HDAC4 in Proben von Human. Er wurde validiert für WB und IF.

Kurzübersicht für HDAC4 Antikörper (pSer246) (Cy7) (ABIN1707521)

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC4 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-HDAC4 Antikörper (Cy7)

Bindungsspezifität: pSer246

Verwendungszweck: Phospho-HDAC4 (Ser246) Polyclonal Antibody, Cy7 Conjugated

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HDAC4 around the phosphorylation site of Ser246

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000), IF(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HDAC4

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Andere Bezeichnung: HDAC4

Hintergrund:

Synonyms: HDAC4Ser246, HDAC4S246, p-HDAC4Ser246, p-HDAC4S246, HD 4, HD4, HDAC 4, HDAC A, HDACA, Histone Deacetylase 4, Histone Deacetylase A, KIAA0288, EC 3.5.1.98, HA6116, HDA4_CAEEL, Histone deacetylase 4, CeHDA-7, Histone deacetylase 7.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

Gen-ID: 9759

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process