TXNDC12 Antikörper (AA 21-120) (Cy5.5)

Produktnummer ABIN1706386

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TXNDC12 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TXNDC12 Antikörper (AA 21-120) (Cy5.5) (ABIN1706386)

Target: TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXNDC12 Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-TXNDC12 Antikörper (Cy5.5)

Bindungsspezifität: AA 21-120

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ERp19

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TXNDC12

Target: TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))

Andere Bezeichnung: ERp19

Hintergrund:

Synonyms: AG1, AGR1, anterior gradient homolog 1, endoplasmic reticulum protein ERp19, endoplasmic reticulum resident protein 18, endoplasmic reticulum resident protein 19, endoplasmic reticulum thioredoxin superfamily member, 18 kDa, ER protein 18, ER protein 19, ERP 18, ERP16, ERP19, hAG 1, hAG1, hTLP19, PDIA16, protein disulfide isomerase family A, member 16, thioredoxin domain containing 12 endoplasmic reticulum, Thioredoxin domain-containing protein 12, thioredoxin like protein p19, TLP19, TXNDC12, TXD12_HUMAN.

Background: Endoplasmic reticulum proteins (ERps) are widely expressed proteins and localize to the ER. ERp19, ERp29, ERp46, ERp57 and ERp72 may act as proteases, protein disulfide isomerases, thiol-disulfide oxidases, phospholipases or a combination of these. ERp19, also designated thioredoxin domain-containing protein 12 (TXNDC12), and ERp46, also designated thioredoxin domain containing 5 (TXNDC5), belong to the thioredoxin superfamily and contain a thioredoxin fold with a consensus active-site sequence (CxxC). Both ERp19 and ERp46 are widely expressed ER luminal proteins that are most abundant in the liver and are enriched in purified liver ER vesicles. ERp19 shows significant protein thiol-disulfide oxidase activity in vitro, which is dependent on the presence of both active-site cysteines.

Gen-ID: 51060

Pathways: Cell RedoxHomeostasis