GnRH2 Antikörper (AA 1-80) (Cy5.5)

Produktnummer ABIN1705448

Der Kaninchen Polyklonal Anti-GnRH2-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, GnRH2 in Proben von Human zu detektieren.

Kurzübersicht für GnRH2 Antikörper (AA 1-80) (Cy5.5) (ABIN1705448)

Target: GnRH2 (Gonadotropin-Releasing Hormone 2 (GnRH2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GnRH2 Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-GnRH2 Antikörper (Cy5.5)

Bindungsspezifität: AA 1-80

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNRH2/GnRH II

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GnRH2

Target: GnRH2 (Gonadotropin-Releasing Hormone 2 (GnRH2))

Andere Bezeichnung: GNRH2

Hintergrund:

Synonyms: GnRH II, GnRH-associated peptide 2, GnRH-associated peptide II, gnrh2, GON2_HUMAN, Gonadoliberin II, Gonadotropin-releasing hormone 2, Gonadotropin-releasing hormone II, LH-RH II, Luliberin II, Luteinizing hormone-releasing hormone II, Progonadoliberin 2, Progonadoliberin II.

Background: Human reproduction is controlled by the hypothalaic-pituitary gonadal axis laid down early in fetal development. Gonadotropin releasing hormone (GnRH), also known as GnRH-associated peptide, luteinizing hormone releasing hormone (LHRH), luliberin or gonadorelin, is a decapeptide that is an important molecule in the hypothalamic-pituitary-gonadal axis control circuit. GnRH is produced by hypothalamic neurons and secreted in a pulsatile manner into the capillary plexus of the medianeminence. GnRH affects the release of lutenizing hormone and follicle stimulating hormone from gonadotropic cells in the anterior pituitary. In addition to hypothalamic GnRH (GnRH I), a second GnRH form (GnRH II) functions primarily in the midbrain. GnRH is expressed in the acrosomal region of human sperm and in the anterior pituitary tissue and cancer cells. Unlike GnRH I, GnRH II is highly expressed outside the brain, particularly in the kidney, bone marrow and prostate, suggesting that it may have multiple functions. GnRH binds to a specific G protein-coupled receptor in the pituitary to regulate synthesis and secretion of gonadotropins.

Gen-ID: 2797

Pathways: Hormone Activity