ARHGEF11 Antikörper (rho Guanine Nucleotide Exchange Factor (GEF) 11) (Cy5)

Details for Product anti-ARHGEF11 Antibody No. ABIN1705076
Antigen
  • ARHGEF11
  • GTRAP48
  • PDZ-RHOGEF
  • B930073M02
  • E130307F09
  • PDZ-RhoGEF
  • Prg
  • RhoGEF
  • mKIAA0380
  • Gtrap48
  • Rho guanine nucleotide exchange factor (GEF) 11
  • Rho guanine nucleotide exchange factor 11
  • rho guanine nucleotide exchange factor 11
  • arhgef11
  • ARHGEF11
  • Arhgef11
  • LOC511220
Reaktivität
Human, Maus, Ratte (Rattus)
74
31
30
5
3
3
3
3
2
1
1
1
Wirt
Kaninchen
67
7
Klonalität
Polyklonal
Konjugat
Dieser ARHGEF11 Antikörper ist konjugiert mit Cy5
5
4
4
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
48
33
20
12
12
4
2
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human PDZ RHOGEF/GTRAP48
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere ARHGEF11 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung PDZ RHOGEF/GTRAP48 (ARHGEF11 Antibody Abstract)
Hintergrund

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

Subcellular location: Cytoplasm

Synonyms: PDZ-RhoGEF, ARHGB_HUMAN, ARHGEF 11, ARHGEF11, DKFZp667F1223, Glutamate transporter EAAT4 associated protein 48, GTRAP 48, GTRAP48, PDZ RhoGEF, Rho guanine exchange factor GEF 11, Rho guanine nucleotide exchange factor GEF 11, Rho guanine nucleotide exchange factor 11, RhoA specic guanine nucleotide exchange factor, RhoGEF glutamate transport modulator.

Pathways Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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