ANO3 Antikörper (Anoctamin 3) (Cy5)

Details for Product anti-ANO3 Antibody No. ABIN1705009
Antigen
  • TMEM16C
  • anoctamin-3
  • C11orf25
  • DYT23
  • DYT24
  • AI838058
  • B230324K02Rik
  • Tmem16c
  • anoctamin 3
  • anoctamin-3
  • ANO3
  • LOC100453980
  • ano3
  • Ano3
Reaktivität
Human, Maus, Ratte (Rattus)
30
26
21
3
3
3
3
2
2
2
1
1
Wirt
Kaninchen
31
Klonalität
Polyklonal
Konjugat
Dieser ANO3 Antikörper ist konjugiert mit Cy5
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
19
12
6
4
3
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human TMEM16C/Anoctamin 3
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere ANO3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Tmem16c/Anoctamin 3 (ANO3 Antibody Abstract)
Hintergrund

TMEM16C is a 981 amino acid multi-pass membrane protein that is encoded by a gene which maps to chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Subcellular location: Extracellular

Synonyms: ANO3, C11orf25, GENX 3947, TMEM16C, Transmembrane protein 16C eight membrane spanning domains, Transmembrane protein 16C, ANO3_HUMAN.

Gen-ID 63982
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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