Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704878
Antigen
  • SRC2
  • c-fgr
  • c-src2
  • p55-Fgr
  • p55c-fgr
  • p58-Fgr
  • p58c-fgr
  • FGR proto-oncogene, Src family tyrosine kinase
  • FGR
  • Fgr
Reaktivität
Human, Maus, Ratte (Rattus)
148
63
34
3
2
1
1
1
1
Wirt
Kaninchen
115
27
20
Klonalität
Polyklonal
Konjugat
Cy5
9
6
5
4
4
4
4
4
3
3
3
3
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
125
78
51
23
12
5
4
3
2
2
Optionen
Immunogen KLH conjugated synthetic peptide derived from human FGR/SRC2
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Fgr/Src2 (FGR Antibody Abstract)
Hintergrund

Src is the human homolog of the v-Src gene of the rous sarcoma virus, also designated avian sarcoma virus or ASV. Src was the first proto-oncogenic non-receptor tyrosine kinase characterized in human. The Src family, which has common structural motifs, is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Src-family kinases transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src-family ki-nases contain an amino-terminal cell membrane anchor followed by an SH3 domain and an SH2 domain, which are involved in modular association and activation, respectively. Src-family kinases, which are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization and membrane trafficking. c-Fgr is a human non-receptor tyrosine kinase family member that was discovered by using a probe toward the v-Fgr portion of the cell-derived domain of Gardner-Rasheed feline sarcoma virus. The human c-Fgr gene encodes a 529 amino acid protein.

Synonyms: c fgr, c fgr protooncogene, c src 2 proto oncogene, c src2, FGR, FLJ43153, Gardner Rasheed feline sarcoma viral v fgr, Gardner Rasheed feline sarcoma viral v fgr oncogene homolog, MGC75096, p55 c fgr protein, P55 FGR, p55c fgr, p58c fgr, Proto oncogene c Fgr, Proto oncogene tyrosine protein kinase FGR, SRC 2, SRC2, Tyrosine protein kinase Fgr, FGR_HUMAN.

Gen-ID 2268
Pathways Sensory Perception of Sound, Stem Cell Maintenance, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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