FOXO4 Antikörper (pThr451) (Cy5)

Produktnummer ABIN1704764

Produktdetails anti-FOXO4 Antikörper (Cy5)

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Bindungsspezifität: pThr451

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXO4 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human FOXO4 around the phosphorylation site of Thr451

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FOXO4

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Andere Bezeichnung: FOXO4 (FOXO4 Produkte)

Synonyme: FOXO4 antikoerper, foxo4 antikoerper, AFX antikoerper, AFX1 antikoerper, MLLT7 antikoerper, Afxh antikoerper, Mllt7 antikoerper, afx antikoerper, RGD1561201 antikoerper, forkhead box O4 antikoerper, forkhead box O4 L homeolog antikoerper, FOXO4 antikoerper, foxo4.L antikoerper, Foxo4 antikoerper

Hintergrund:

Synonyms: FOXO4 phospho T451,p-FOXO4 phospho T451, AFXSer197, Fork head domain transcription factor AFX1, AFX, AFX1, Afxh, ALL1-fused gene from X chromosome, Fork head domain transcription factor AFX1, Forkhead box O4, Forkhead box protein O4, FOXO 4, Mixed lineage leukemia, translocated to, 7, MLLT7, Myeloid lymphoid or mixed lineage leukemia translocated to 7, Myeloid/lymphoid or mixed lineage leukemia, translocated to, 7, Putative fork head domain transcription factor AFX1, FOXO4_HUMAN.

Background: FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.

Gen-ID: 4303

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation