Androgen Receptor Antikörper (AR) (pSer791) (Cy5)

Details for Product anti-AR Antibody No. ABIN1704526
Antigen
  • AIS
  • DHTR
  • HUMARA
  • HYSP1
  • KD
  • NR3C4
  • SBMA
  • SMAX1
  • TFM
  • AW320017
  • Tfm
  • Andr
  • AR
  • androgen receptor
  • AR
  • Ar
  • ar
Epitop
pSer791
49
42
38
36
25
23
22
21
19
18
15
15
12
11
10
9
9
9
9
9
8
8
8
6
6
6
5
5
5
5
5
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
618
148
126
19
12
7
5
4
4
4
1
1
1
1
1
Wirt
Kaninchen
439
185
19
2
1
Klonalität
Polyklonal
Konjugat
Dieser Androgen Receptor Antikörper ist konjugiert mit Cy5
35
16
14
13
13
13
13
13
12
12
12
10
5
5
5
5
5
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
331
205
168
129
109
66
64
63
26
17
15
15
8
7
5
4
3
3
3
2
1
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human Androgen Receptor around the phosphorylation site of Ser791
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere Androgen Receptor products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Androgen Receptor (AR Antibody Abstract)
Hintergrund

The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Synonyms: Androgen Receptor phospho S791, Androgen Receptor Ser791, Androgen Receptor phospho Ser791, p-Androgen Receptor Ser791, ANDR_HUMAN, HYSP1, AIS, Androgen receptor dihydrotestosterone receptor, testicular feminization, spinal and bulbar muscular atrophy, Kennedy disease, AR, DHTR, Dihydro Testosterone Receptor, Dihydrotestosterone receptor, HUMARA, Nuclear receptor subfamily 3 group C member 4, SBMA, SMAX1, Spinal and bulbar muscular atrophy, TFM.

Gen-ID 367
Pathways Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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