PRNP Antikörper (Prion Protein) (Cy5)

Details for Product anti-PRNP Antibody No. ABIN1704516
Antigen
  • ASCR
  • AltPrP
  • CD230
  • CJD
  • GSS
  • KURU
  • PRIP
  • PrP
  • PrP27-30
  • PrP33-35C
  • PrPc
  • p27-30
  • Prn
  • Prn-p
  • prp
  • cjd
  • prion
  • prp(c)
  • MGC84114
  • PRP
  • PRPC
  • Prp
  • SIP
  • PRNP
  • AA960666
  • AI325101
  • PrP
  • PrPC
  • PrPSc
  • Prn-i
  • Sinc
  • prP27-30
  • prP33-35C
  • PrP-1
  • PrP1
  • prnprs1
  • stPrP-1
  • zgc:123004
  • prion protein
  • prion protein S homeolog
  • prion protein b
  • PRNP
  • Prnp
  • prnp.S
  • prnpb
Reaktivität
Human, Maus, Ratte (Rattus)
153
85
82
37
24
4
2
2
2
1
1
1
1
Wirt
Kaninchen
131
46
24
3
Klonalität
Polyklonal
Konjugat
Dieser PRNP Antikörper ist konjugiert mit Cy5
10
6
6
5
5
5
5
5
4
2
2
2
2
2
2
2
2
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
137
79
57
36
25
17
9
7
7
5
5
4
3
Optionen
Immunogen KLH conjugated synthetic peptide derived from human Major prion protein
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere PRNP products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Prion Protein PrP (PRNP Antibody Abstract)
Hintergrund

The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].

Synonyms: AltPrP, ASCR, atal familial insomnia, CD230, CD230 antigen, CJD, Creutzfeld Jakob disease, Gerstmann-Strausler-Scheinker syndrome, GSS, KURU, Major prion protein, MGC26679, p27 30, PRIO_HUMAN, Prion protein, Prion related protein, PRIP, Prni, Prnp, PrP, PrP27 30, PrP27-30, PrP33 35C, PrP33-35C, PrPC, PrPSc, Sinc.
Pathways Transition Metal Ion Homeostasis, Activated T Cell Proliferation
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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