G6PC2 Antikörper (Glucose-6-Phosphatase, Catalytic, 2) (Cy5)

Details for Product anti-G6PC2 Antibody No. ABIN1704500
Antigen
  • IGRP
  • G6pc-rs
  • Igrp
  • g6pc2
  • igrp
  • glucose-6-phosphatase catalytic subunit 2
  • glucose-6-phosphatase, catalytic, 2
  • glucose-6-phosphatase, catalytic, 2 S homeolog
  • G6PC2
  • G6pc2
  • g6pc2.S
Reaktivität
Human, Maus, Ratte (Rattus)
18
14
14
Wirt
Kaninchen
18
Klonalität
Polyklonal
Konjugat
Dieser G6PC2 Antikörper ist konjugiert mit Cy5
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
12
4
3
3
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2/IGRP
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere G6PC2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Glucose 6 Phosphatase 2/Igrp
Hintergrund

Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-alpha, a second form, designated G6Pase-â^, contributes to blood glucose homeostasis in a wider range of tissues. Islet-specific G-6-Pase catalytic subunit-related protein (IGRP), a homolog of the catalytic subunit of G6Pase, may play a role in the regulation of islet metabolism and in insulin secretion induced by metabolites. The exact catalytic acivity of IGRP is not defined. Identification of inhibitors of IGRP have potential therapeutic benefits for treatment of type 2 diabetes resulting from insulin secretion defects. Structurally, IGRP has been shown to be a glycoprotein held in the endoplasmic reticulum by nine transmembrane domains, which are then degraded in cells through the proteasome pathway generating MHC class I presented peptides.

Synonyms: G 6 Pase 2, G 6 Pase2, G6Pase 2, G6Pase2, G6PC 2, G6pc rs, G6pcrs, Glucose 6 phosphatase 2, Glucose 6 phosphatase, catalytic, 2, Glucose 6 phosphatase, catalytic, related, Glucose 6 phosphate catalytic 2, Islet specic G6CP related protein, Islet specic glucose 6 phosphatase, Islet specic glucose 6 phosphatase catalytic subunit related protein, G6PC2_HUMAN.

Gen-ID 57818
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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