CRTC3 Antikörper (AA 151-260) (Cy5)

Produktnummer ABIN1704473

Der Kaninchen Polyklonal Anti-CRTC3-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, CRTC3 in Proben von Human zu detektieren.

Kurzübersicht für CRTC3 Antikörper (AA 151-260) (Cy5) (ABIN1704473)

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRTC3 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CRTC3 Antikörper (Cy5)

Bindungsspezifität: AA 151-260

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRTC3/TORC3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CRTC3

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Andere Bezeichnung: CRTC3/TORC3

Hintergrund:

Synonyms: CREB regulated transcription coactivator 3, CREB-regulated transcription coactivator 3, CRTC 3, CRTC3, CRTC3_HUMAN, FLJ21868, TORC 3, TORC-3, TORC3, Transducer of CREB protein 3, Transducer of regulated cAMP response element binding protein CREB 3, Transducer of regulated cAMP response element binding protein 3, Transducer of regulated cAMP response element-binding protein 3, Transducer of regulated CREB protein 3.

Background: TORC3 is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC signaling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells.

Gen-ID: 64784

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion