CRTC3 Antikörper (AA 151-260) (Cy5)
Kurzübersicht für CRTC3 Antikörper (AA 151-260) (Cy5) (ABIN1704473)
Target
Alle CRTC3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 151-260
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Homologie
- Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human CRTC3/TORC3
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
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Andere Bezeichnung
- CRTC3/TORC3
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Hintergrund
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Synonyms: CREB regulated transcription coactivator 3, CREB-regulated transcription coactivator 3, CRTC 3, CRTC3, CRTC3_HUMAN, FLJ21868, TORC 3, TORC-3, TORC3, Transducer of CREB protein 3, Transducer of regulated cAMP response element binding protein CREB 3, Transducer of regulated cAMP response element binding protein 3, Transducer of regulated cAMP response element-binding protein 3, Transducer of regulated CREB protein 3.
Background: TORC3 is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC signaling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells.
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Gen-ID
- 64784
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Pathways
- SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
Target
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