beta Catenin Antikörper (Catenin, beta) (pSer37) (Cy5)

Details for Product anti-Catenin, beta Antibody No. ABIN1704408
Antigen
  • Bfc
  • Catnb
  • Mesc
  • CTNNB
  • MRD19
  • armadillo
  • ctnnb
  • id:ibd2058
  • wu:fb73e10
  • wu:fi81c06
  • wu:fk25h01
  • beta-catenin
  • ctnnb1
  • CHBCAT
  • catenin (cadherin associated protein), beta 1
  • catenin beta 1
  • catenin (cadherin-associated protein), beta 1
  • catenin beta 1 L homeolog
  • Ctnnb1
  • CTNNB1
  • ctnnb1
  • ctnnb1.L
Epitop
pSer37
64
51
48
47
46
41
19
18
16
15
15
15
13
8
7
6
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
674
512
453
108
92
89
14
13
12
12
7
6
3
2
2
2
2
1
1
1
1
Wirt
Kaninchen
437
242
4
3
1
Klonalität
Polyklonal
Konjugat
Dieser beta Catenin Antikörper ist konjugiert mit Cy5
26
16
15
15
15
15
15
14
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
7
7
7
7
7
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
508
270
258
229
109
93
77
44
26
21
13
13
5
4
1
1
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human beta Catenin around the phosphorylation site of Ser37
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere beta Catenin products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung beta Catenin
Hintergrund

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009].

Synonyms: beta Catenin phospho S37, beta Catenin phospho Ser37, p-beta Catenin S37, p-beta Catenin Ser37, p-beta Catenin phospho S37, beta-catenin, beta catenin, CTNNB1, CHBCAT, CTNNB1, CTNNB, PRO2286, Cadherin associated protein, Catenin cadherin associated protein, beta 1, 88 kDa, Catenin beta 1, Catenin beta-1, CATNB, CTNB1_HUMAN, CTNNB, CTNNB1, DKFZp686D02253, FLJ25606, FLJ37923, b-catenin, OTTHUMP00000162082, OTTHUMP00000165222, OTTHUMP00000165223, OTTHUMP00000209288, OTTHUMP00000209289..

Gen-ID 1499
Pathways Peptide Hormone Metabolism
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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