RASA1 Antikörper (RAS P21 Protein Activator (GTPase Activating Protein) 1) (Cy5)

Details for Product anti-RASA1 Antibody No. ABIN1704347
Antigen
  • CG9209
  • D-RasGAP
  • Dmel\\CG9209
  • RAS-GAP
  • RasGAP
  • RasGap
  • rasGap
  • CM-AVM
  • CMAVM
  • GAP
  • PKWS
  • RASA
  • RASGAP
  • p120GAP
  • p120RASGAP
  • GAPX
  • Rasa
  • Gap
  • vacuolar peduncle
  • RAS p21 protein activator 1
  • vap
  • RASA1
  • Rasa1
Reaktivität
Human, Maus, Ratte (Rattus)
113
59
57
5
2
2
2
2
2
2
1
1
1
Wirt
Kaninchen
92
20
2
1
Klonalität
Polyklonal
Konjugat
Dieser RASA1 Antikörper ist konjugiert mit Cy5
6
5
5
3
3
3
3
3
2
2
2
2
2
2
2
2
2
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
79
36
25
16
16
9
8
2
2
1
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human Ras GTPase-activating protein 1
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere RASA1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Rasa1 (RASA1 Antibody Abstract)
Hintergrund

The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1,2). p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3). Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their excitation period, hydrolysis of their bound GTP to GDP, is impaired as a result of specific mutations (3). Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4,5). The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity (6,7), and proteins that stimulate the GTPase activity of three other low molecular weight GTPases, including Rho, Rab 3A and Rap 1, have also been described (8,9).

Synonyms: Ras GAP, CM AVM, CMAVM, DKFZp434N071, GAP, GTPase activating protein, GTPase-activating protein, OTTHUMP00000222390, OTTHUMP00000222391, OTTHUMP00000222392, OTTHUMP00000222393, p120GAP, p120RASGAP, PKWS, Ras GTPase-activating protein 1, RAS p21 protein activator GTPase activating protein 1, Ras p21 protein activator, RASA, RASA1, RASA1_HUMAN, RasGAP, Triphosphatase activating protein.

Gen-ID 5921
Pathways Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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