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RASA1 Antikörper (RAS P21 Protein Activator (GTPase Activating Protein) 1) (Cy5) Primary Antibody

RASA1 Reaktivität: Human, Maus, Ratte IF (p) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN1704347
$442.20
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 16 Werktagen
  • Target
    RASA1
    Reaktivität
    Human, Maus, Ratte
    • 64
    • 28
    • 26
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Wirt
    Kaninchen
    Klonalität
    Polyklonal
    Konjugat
    Dieser RASA1 Antikörper ist konjugiert mit Cy5
    • 34
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Applikation
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • 47
    • 28
    • 13
    • 10
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Ras GTPase-activating protein 1
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 4°C
    Haltbarkeit
    12 months
  • Target
    RASA1
    Andere Bezeichnung
    Rasa1 (RASA1 Antibody Abstract)
    Synonyme
    CG9209, D-RasGAP, Dmel\\CG9209, RAS-GAP, RasGAP, RasGap, rasGap, CM-AVM, CMAVM, GAP, PKWS, RASA, RASGAP, p120GAP, p120RASGAP, GAPX, Rasa, Gap, vacuolar peduncle, RAS p21 protein activator 1, vap, RASA1, Rasa1
    Hintergrund

    The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1,2). p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3). Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their excitation period, hydrolysis of their bound GTP to GDP, is impaired as a result of specific mutations (3). Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4,5). The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity (6,7), and proteins that stimulate the GTPase activity of three other low molecular weight GTPases, including Rho, Rab 3A and Rap 1, have also been described (8,9).

    Synonyms: Ras GAP, CM AVM, CMAVM, DKFZp434N071, GAP, GTPase activating protein, GTPase-activating protein, OTTHUMP00000222390, OTTHUMP00000222391, OTTHUMP00000222392, OTTHUMP00000222393, p120GAP, p120RASGAP, PKWS, Ras GTPase-activating protein 1, RAS p21 protein activator GTPase activating protein 1, Ras p21 protein activator, RASA, RASA1, RASA1_HUMAN, RasGAP, Triphosphatase activating protein.

    Gen-ID
    5921
    Pathways
    Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
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