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ARID1B Antikörper (AA 1501-1600) (Cy5)

ARID1B Reaktivität: Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN1704160
  • Target Alle ARID1B Antikörper anzeigen
    ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
    Bindungsspezifität
    • 14
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1501-1600
    Reaktivität
    • 32
    • 19
    • 14
    • 3
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 44
    • 2
    Kaninchen
    Klonalität
    • 44
    • 2
    Polyklonal
    Konjugat
    • 19
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARID1B Antikörper ist konjugiert mit Cy5
    Applikation
    • 27
    • 12
    • 12
    • 12
    • 10
    • 9
    • 9
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ARID1B
    Isotyp
    IgG
    Top Product
    Discover our top product ARID1B Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
    Andere Bezeichnung
    ARID1B (ARID1B Produkte)
    Synonyme
    fd07d11 antikoerper, si:dkey-60a16.3 antikoerper, wu:fd07d11 antikoerper, 8030481M12 antikoerper, 9330189K18Rik antikoerper, AI836955 antikoerper, Ardi1b antikoerper, B230217J03Rik antikoerper, mKIAA1235 antikoerper, 6A3-5 antikoerper, Smcf1 antikoerper, smcf-1 antikoerper, BAF250B antikoerper, BRIGHT antikoerper, DAN15 antikoerper, ELD/OSA1 antikoerper, MRD12 antikoerper, OSA2 antikoerper, P250R antikoerper, AT rich interactive domain 1B (SWI1-like) antikoerper, AT rich interactive domain 1B (SWI-like) antikoerper, AT-rich interaction domain 1B antikoerper, arid1b antikoerper, Arid1b antikoerper, ARID1B antikoerper
    Hintergrund

    Synonyms: OSA2, 6A3-5, DAN15, MRD12, P250R, BRIGHT, BAF250B, ELD/OSA1, AT-rich interactive domain-containing protein 1B, ARID domain-containing protein 1B, BRG1-associated factor 250b, BRG1-binding protein hELD/OSA1, Osa homolog 2, hOsa2, ARID1B, KIAA1235

    Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically.

    Gen-ID
    57492
    UniProt
    Q8NFD5
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