EEF2K Antikörper (Eukaryotic Elongation Factor-2 Kinase) (pSer359) (Cy5)

Details for Product anti-EEF2K Antibody No. ABIN1704156
Antigen
  • HSU93850
  • eEF-2K
  • C86191
  • SMEF2K
  • eEF-2 kinase
  • cb365
  • fa04b08
  • wu:fa04b08
  • zgc:100973
  • eukaryotic elongation factor 2 kinase
  • eukaryotic elongation factor-2 kinase
  • EEF2K
  • Eef2k
  • eef2k
  • LOC101930123
Epitop
pSer359
22
20
13
10
7
4
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
113
80
73
5
3
3
3
3
2
2
Wirt
Kaninchen
128
3
Klonalität
Polyklonal
Konjugat
Dieser EEF2K Antikörper ist konjugiert mit Cy5
6
4
4
3
3
3
3
3
2
2
2
2
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
95
58
41
20
17
13
7
6
4
1
1
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human EEF2k around the phosphorylation site of Ser359
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere EEF2K products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Eef2k (EEF2K Antibody Abstract)
Hintergrund

Eukaryotic elongation factor 2 kinase (EEF2k) previously known as Ca2+/calmodulin dependent protein kinase III, is an abundant cytoplasmic protein highly specific for elongation factor 2 (eEf2). Phosphorylation of eEF2 by eEF2 kinase on specific threonine residues results in the inactivation of eEF-2 and in termination of mRNA translation. The activity of eEF2 kinase is not only dependent upon Ca2+ ions, calmodulin (CaM) and insulin, but is also regulated both negatively and positively via phosphorylation by different protein kinases (AMPK, S6K1, p90 RSK). There is also evidence that eEF-2 phosphorylation is involved in the regulation of cell cycle progression, cellular differentiation, oogensis and malignant tumors.

Synonyms: EEF2K phospho S359, p-EEF2K phospho S359, Calcium/calmodulin dependent eukaryotic elongation factor 2, Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase, Calmodulin dependent protein kinase III, cb365, eEF 2 kinase, eEF 2K, EEF2K protein, Elongation factor 2 kinase, Eukaryotic elongation factor 2 kinase, kinase eEF2K, SMEF2K, EF2K_HUMAN.

Gen-ID 29904
Pathways AMPK Signaling
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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